Histone deacetylase inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Histone deacetylase (HDAC) inhibitors are a group of agents that inhibit the histone deactylase enzymes. During gene expression DNA coils and uncoils around histones. Histone acetylases, acetylate the lysine residues in core histones and histone deactylases remove the acetyl groups from the lysine residues. These actions are important in the regulation of gene expression.

Histone deacetylase inhibitors prevent the deactylation, affect gene expression and causes apoptosis of tumor cells. Histone deacetylase inhibitors are used to treat cutaneous T-cell lymphoma.

See also

Medical conditions associated with histone deacetylase inhibitors:

• Cutaneous T-cell Lymphoma
• Peripheral T-cell Lymphoma

Drug List:

Istodax

Zolinza

Hormone replacement therapy

Hormone replacement therapy involves supplementing female hormones for the relief of symptoms resulting from an end in ovarian function, either following surgical removal of the ovaries or after natural menopause.

Estrogens can be prescribed alone or in combination with progestins. A combination of estrogen and progestin is preferred if the woman has her uterus as estrogen alone can over stimulate the endometrium causing uterine bleeding. Hormone replacement therapy is effective in controlling symptoms such as hot flashes, vaginal dryness, psychological well-being and in preventing osteoporosis.

Drug List:

H2 antagonists

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

H2 antagonists competitively inhibits histamine at the H2 receptors and leads to a reduction in secretion of gastric acid.

Histamine stimulates the secretion of gastric acid by action on H2 receptors, which are found in the parietal cells of the gastric mucosa.

H2 antagonists are used to treat gastroesophageal reflux disease (GERD), gastrointestinal ulcers and other gastrointestinal hypersecretory conditions.

See also

Medical conditions associated with H2 antagonists:

• Allergic Urticaria
• Duodenal Ulcer
• Duodenal Ulcer Prophylaxis
• Erosive Esophagitis
• Gastric Ulcer Maintenance Treatment
• Gastrointestinal Hemorrhage
• GERD
• Human Papilloma Virus
• Indigestion
• Lung Cancer
• Obesity
• Pathological Hypersecretory Conditions
• Peptic Ulcer
• Stomach Ulcer
• Stress Ulcer Prophylaxis
• Surgical Prophylaxis
• Upper GI Hemorrhage
• Urticaria
• Zollinger-Ellison Syndrome

Drug List:

Axid-Ar

Tagamet

Pepcid-Ac-Chewable-Tablets

Pepcid-Ac

Zantac

Zantac-75

Zantac-150

Pepcid

Tagamet-Hb

Axid

Acid-Controller-Complete-Dual-Action

Acid-Controller-Original-Strength

Axid-Pulvules

Berkley-And-Jensen-Acid-Controller-Maximum-Strength

Berkley-And-Jensen-Acid-Reducer-Maximum-Strength

Careone-Acid-Reducer

Deprizine

Dual-Action-Complete

Equaline-Acid-Reducer

Equaline-Heartburn-Relief

Fluxid

Heartburn-Relief

Leader-Acid-Reducer

Mylanta-Ar

Pepcid-Ac-Maximum-Strength

Pepcid-Ac-Maximum-Strength-Tablets

Pepcid-Complete

Pepcid-Oral-Suspension

Pepcid-Rpd

Sunmark-Acid-Reducer-Maximum-Strength

Taladine

Tritec

Zantac-25-Mg-Efferdose-Effervescent-Tablets

Zantac-150-Efferdose-Effervescent-Tablets

Zantac-300

Zantac-Efferdose

Heparins

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Heparin is an injectable anticoagulant that activates antithrombin III, which inhibits thrombin and factor Xa, factors necessary in the final stages of blood clotting cascade.

There are two types of heparins: high molecular weight heparins and low molecular weight heparins.

High molecular weight heparins require daily blood monitoring to check the aPTT. Low molecular weight heparins give a better anticoagulant response and do not need daily blood monitoring.

Heparin is used to treat or prevent clots in conditions where there is a high risk of clot formation and thromboembolism, such as in atrial fibrillation, myocardial infarction, deep vein thrombosis, knee and hip surgery and so on.

See also

Medical conditions associated with heparins:

• Acute Coronary Syndrome
• Angina
• Anticoagulation During Pregnancy
• Antiphospholipid Syndrome
• Deep Vein Thrombosis
• Deep Vein Thrombosis Prophylaxis after Abdominal Surgery
• Deep Vein Thrombosis Prophylaxis after Hip Replacement Surgery
• Deep Vein Thrombosis Prophylaxis after Knee Replacement Surgery
• Deep Vein Thrombosis Prophylaxis after Orthopedic Surgery
• Deep Vein Thrombosis, Prophylaxis
• Heart Attack
• Patency Maintenance of Indwelling Intravenous Devices
• Pulmonary Embolism
• Thrombotic/Thromboembolic Disorder
• Venous Thromboembolism

Drug List:

Fragmin

Innohep

Lovenox

Normiflo

Heparin-Lock-Flush

Heparin-Sodium

Orgaran

HER2 inhibitors

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Human epidermal growth factor receptor (HER2) inhibitors are either tyrosine kinase inhibitors or monoclonal antibodies that slow down or stop cell growth.

Human epidermal growth factor receptors are transmembrane receptors; they have an extracellular binding component, a transmembrane component and an intracellular tyrosine kinase component. Some breast cancers have an over-expression of HER2 resulting in increased cell growth and spread of cancer cells.

Tyrosine kinase inhibitors bind to the tyrosine kinase domain in the HER2 and stops activation of the signaling pathway. Monoclonal antibodies bind to the extracellular component of the HER2, prevent the actual substrates from binding to the receptors and stop the receptor activation.

HER2 inhibitors are used in the treatment of breast cancer.

See also

Medical conditions associated with HER2 inhibitors:

• Breast Cancer
• Breast Cancer, Adjuvant
• Breast Cancer, Metastatic
• Esophageal Carcinoma
• Gastric Cancer
• Salivary Gland Cancer

Drug List:

Herceptin

Tykerb

Hematopoietic stem cell mobilizer

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Hematopoietic stem cell mobilizer binds to the CXCR4 chemokine receptor and inhibits the binding of its ligand, stromal cell-derived factor-1-alpha (SDF-1-alpha). This leads to mobilization of hematopoietic stem cells to the peripheral blood.

The hematopoietic stem cells (CD34+ cells) are collected from the peripheral blood and used for autologous transplantation in patients with non-Hodgkins

See also

Medical conditions associated with hematopoietic stem cell mobilizer:

• Multiple Myeloma
• Non-Hodgkin's Lymphoma

Drug List:

Mozobil

Hormones/antineoplastics

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

See also

Medical conditions associated with hormones/antineoplastics:

• Abnormal Uterine Bleeding
• AIDS Related Wasting
• Amenorrhea
• Anorexia
• Birth Control
• Bleeding Disorder
• Breast Cancer
• Breast Cancer, Adjuvant
• Breast Cancer, Male
• Breast Cancer, Metastatic
• Breast Cancer, Palliative
• Breast Cancer, Prevention
• Cachexia
• Delayed Puberty, Male
• Endometrial Cancer
• Endometrial Hyperplasia
• Endometrial Hyperplasia, Prophylaxis
• Endometriosis
• Female Infertility
• Hirsutism
• Hot Flashes
• Hypogonadism, Male
• McCune-Albright Syndrome
• Osteoporosis
• Postmenopausal Symptoms
• Precocious Puberty
• Prevention of Osteoporosis
• Prostate Cancer
• Pubertal Gynecomastia
• Renal Cell Carcinoma
• Uterine Fibroids
• Weight Loss

Drug List:

Faslodex

Lupron-Depot-11-25-Mg-Depot-Suspension

Megace_Es

Trelstar-La

Lupron-Depot

Megace-Suspension

Lupron

Evista

Femara

Lupron-Depot-Ped-Kit

Nolvadex

Provera

Lupron-Depot-3-75-Mg-Suspension

Arimidex

Depo-Provera-Contraceptive-Injectable

Casodex

Depo-Provera

Aromasin

Zoladex

Supprelin-La-Implant

Eligard

Androxy

Depo-Subq-Provera-104-Injectable-Suspension-Subcutaneous

Emcyt

Eulexin

Fareston

Firmagon

Halotestin

Lupron-Depot-Gyn

Nilandron

Plenaxis

Soltamox-Solution

Teslac

Trelstar

Trelstar-Depot

Vantas

Viadur-Implant

Heparin antagonists

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

See also

Medical conditions associated with heparin antagonists:

• Heparin Overdose

Drug List:

Protamine-Sulfate

H. pylori eradication agents

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Agents used in treatment of Helicobacter Pylori are medicines used for stomach acid inhibition, combined with antibacterial agents. Treatment is for one week with a proton pump inhibitor or an antacid (or antisecretory agents), and two appropriate antibacterial agents. This one week triple therapy does give a good eradication rate.

See also

Medical conditions associated with H. pylori eradication agents:

• Helicobacter Pylori Infection

Drug List:

Prevpac-Therapy-Pack

Pylera

Helidac-Therapy-Pack

Hydantoin anticonvulsants

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Hydantoin anticonvulsants are structurally related to barbiturates. They have an allantoin heterocyclic base. Hydantoins slow the synaptic transmission by blocking sodium channels from recovering from the inactivated state, and inhibits neurons from firing. This stops the repeated excitation of cells that results in seizures.

Hydantoin anticonvulsants are used to treat a wide range of seizures types.

See also

Medical conditions associated with hydantoin anticonvulsants:

• Anxiety
• Arrhythmia
• Epilepsy
• Neurosurgery
• Peripheral Neuropathy
• Rheumatoid Arthritis
• Seizure Prevention
• Seizures
• Status Epilepticus
• Trigeminal Neuralgia

Drug List:

Phenytoin-Sodium-Prompt

Phenytek-Extended-Release-Capsules

Dilantin

Cerebyx

Mesantoin

Peganone

Hormones

Hormone is a chemical substance that is produced in one part of the body (by an endocrine gland) and is carried in the blood to other distant organs or tissues where it acts to modify their structure or function. Some cells release hormones that induce a response in the neighboring cells (paracrine function), or sometimes the hormones can act on the cells they are released from (autocrine function).

For a cell to respond to a particular hormone it needs to have specific receptors for that hormone, and once the hormone binds to the receptor specific chemical pathways are activated that lead to a response.

Examples of hormones are corticosteroids (from the adrenal cortex), growth hormone (from the pituitary gland) and androgens (from the testes).

See also

• adrenal cortical steroids
  • corticotropin
  • glucocorticoids
  • mineralocorticoids
• adrenal corticosteroid inhibitors
• amylin analogs
• antiandrogens
• antidiuretic hormones
• antigonadotropic agents
• antithyroid agents
• aromatase inhibitors
• bisphosphonates
• calcitonin
• estrogen receptor antagonists
• gonadotropin-releasing hormone antagonists
• growth hormone receptor blockers
• growth hormones
• incretin mimetics
• insulin-like growth factor
• miscellaneous hormones
• parathyroid hormone and analogs
• progesterone receptor modulators
• prolactin inhibitors
• selective estrogen receptor modulators
• sex hormones
  • 5-alpha-reductase inhibitors
  • androgens and anabolic steroids
  • contraceptives
  • estrogens
  • gonadotropin releasing hormones
  • gonadotropins
  • hormone replacement therapy
  • miscellaneous sex hormones
  • progestins
  • sex hormone combinations
• somatostatin and somatostatin analogs
• synthetic ovulation stimulants
• thyroid drugs

Drug List:

Herbal products

A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Herbal products are medicines derived from plants. They are used as supplements to improve health and well being, and may be used for other therapeutic purposes. Herbal products are available as tablets, capsules, powders, extracts, teas and so on.

Herbal medicines are thought to be safe as it is natural, but in fact it can cause serious adverse effects and interaction with other drugs and supplements.

See also

Medical conditions associated with herbal products:

• Acne
• ADHD
• Allergies
• Anemia
• Anorexia
• Anxiety
• Anxiety and Stress
• Aphthous Ulcer
• Asthma
• Atopic Dermatitis
• Bacterial Infection
• Bacterial Skin Infection
• Benign Prostatic Hyperplasia
• Bronchitis
• Burns, External
• Cancer
• Chronic Fatigue Syndrome
• Cold Sores
• Cold Symptoms
• Condylomata Acuminata
• Constipation
• Constipation, Chronic
• Coronary Artery Disease
• Cough
• Depression
• Dermatitis
• Diabetes, Type 1
• Diabetes, Type 2
• Diabetic Nerve Damage
• Diarrhea
• Diarrhea, Acute
• Diarrhea, Chronic
• Dry Skin
• Eczema
• Enuresis
• Epicondylitis, Tennis Elbow
• Epilepsy
• Erectile Dysfunction
• Eye Dryness/Redness
• Eye Redness/Itching
• Fever
• Fibromyalgia
• Gallbladder Disease
• Gas
• GERD
• Gingivitis
• Gout
• Headache
• Heart Disease
• Hemorrhoids
• Herbal Supplementation
• High Blood Pressure
• High Cholesterol
• Hot Flashes
• Human Papilloma Virus
• Indigestion
• Infectious Gastroenteritis
• Inflammatory Conditions
• Influenza
• Insomnia
• Labor Induction
• Labor Pain
• Liver Cirrhosis
• Menopausal Disorders
• Menstrual Disorders
• Migraine
• Migraine Prevention
• Mild Cognitive Impairment
• Motion Sickness
• Muscle Pain
• Muscle Spasm
• Nasal Congestion
• Nausea/Vomiting
• Neuralgia
• Night Terrors
• Nocturnal Leg Cramps
• Nonalcoholic Fatty Liver Disease
• Obesity
• Oral and Dental Conditions
• Osteoarthritis
• Otitis Externa
• Overactive Bladder
• Peripheral Neuropathy
• Photoaging of the Skin
• Postmenopausal Symptoms
• Premenstrual Dysphoric Disorder
• Prostate Cancer
• Psoriasis
• Rheumatoid Arthritis
• Rhinorrhea
• Sciatica
• Sedation
• Sinus Symptoms
• Sinusitis
• Sjogren's Syndrome
• Skin and Structure Infection
• Skin Infection
• Skin Rash
• Smallpox Prophylaxis
• Stomach Ulcer
• Strep Throat
• Sunburn
• Systemic Lupus Erythematosus
• Tonsillitis/Pharyngitis
• Upper Respiratory Tract Infection
• Urinary Incontinence
• Urinary Tract Infection
• Urticaria
• Varicose Veins
• Vomiting
• Weight Loss

Drug List:

Azo-Cranberry

Evening-Primrose-Oil

5-Htp

Carrington-Oral-Wound-Rinse

Ginkgo-Biloba

Menopause-Support

Oramagic-Rx

Primrose-Oil

Venastat