Friday, September 30, 2016

CD20 monoclonal antibodies


A drug may be classified by the chemical type of the active ingredient or by the way it is used to treat a particular condition. Each drug can be classified into one or more drug classes.

Monoclonal antibodies used in immunotherapy are produced artificially from a cell clone therefore consist of a single type of immunoglobulin. They are targeted towards specific antigens and bind to the antigens to form a complex. The complex can be recognized and destroyed by phagocytes or used for other diagnostic purposes.


Natural antibodies are proteins made by the B-lymphocytes in response to antigens. Each B-cell makes only one type of antibody. For therapeutic purposes a significant amount of a particular antibody is needed. These are obtained from a culture that gives a one type of antibody, which are called monoclonal antibodies.


CD20 monoclonal antibodies are targeted against B-cell antigens, and are used in the treatment of B-cell Non-Hodgkin

See also

Medical conditions associated with CD20 monoclonal antibodies:

  • Bullous Pemphigoid
  • Chronic Lymphocytic Leukemia
  • Diagnosis and Investigation
  • Evan's Syndrome
  • Focal Segmental Glomerulosclerosis
  • Follicular Lymphoma
  • Idiopathic Thrombocytopenic Purpura
  • Microscopic polyangiitis
  • Non-Hodgkin's Lymphoma
  • Pemphigoid
  • Pemphigus
  • Rheumatoid Arthritis
  • Wegener's Granulomatosus

Drug List:

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